The recent Neuron article, “Genetic Background Limits Generalizability of Genotype-Phenotype Relationships”, has garnered considerable attention on various social media outlets! No doubt helped by the accompanying whimsical video abstract, “Should Single Strains Suffice?”, starring Drs. Laura Sittig, Abraham Palmer, and Abe’s 1977 VW van. It’s been retweeted many times and covered by blogs. Altmetric ranks it in the top 5% of all scientific articles, ranked by attention or similar age.