Publications

Baggott MJ, Childs E, Hart AB, de Bruin E, Palmer AA, Wilkinson JE, de Wit H. Psychopharmacology of theobromine in healthy volunteers. Psychopharmacology, 2013, Feb 19. [Epub ahead of print]

Distler MG, Gorfinkle N, Papale LA, Wuenschell GE, Termini J, Escayg A, Winawer, MR, Palmer AA. Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility. Epilepsia, 2013, Feb 14. [Epub ahead of print]

Hart AB, de Wit H, Palmer AA. Candidate gene studies of intermediate phenotypes: failure to replicate. Neuropsychopharm, 2013 Apr;38(5):802-16.

Distler MG, Opal M, Dulawa, SC, Palmer AA. Assessment of behaviors modeling aspects of schizophrenia in Csmd1 mutant mice. PLoS ONE, 2012, 7(12): e51235,

Cheng R, Palmer AA. A Simulation Study of Permutation, Bootstrap, and Gene Dropping for Assessing Statistical Significance in the Case of Unequal Relatedness. Genetics,  2013 Mar;193(3):1015-8

Wardle, MC, Hart AB, Palmer AA, de Wit H. Does COMT genotype influence the effects of d-amphetamine on executive functioning? Genes Brain and Behavior, 2013 Feb;12(1):13-20

Distler MG, Opal M, Dulawa, SC, Palmer AA. Role of Glyoxalase 1 (Glo1) and methylglyoxal (MG) in behavior: recent advances and mechanistic insights. Front Genet. 2012;3:250. Epub 2012 Nov 19.

Hart AB, Engelhardt BE, Wardle MC, Sokoloff G, Stephens M, de Wit H, Palmer AA. Genome-Wide Association Study of d-Amphetamine Response in Healthy Volunteers Identifies Putative Associations, Including Cadherin 13 (CDH13). PLoS One. 2012;7(8):e42646. Epub 2012 Aug 28.

Bryant CD, Kole LA, Guido MA, Cheng R, Palmer AA. Methamphetamine-induced conditioned place preference in LG/J and SM/J mouse strains and an F45/F46 advanced intercross line. Front Genet. 2012;3:126. Epub 2012 Jul 11.

Distler MG, Plant LD, Sokoloff G, Hawk AJ, Aneas I, Wuenschell GE, Termini J, Meredith SC, Nobrega MA, Palmer AA. Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal. J Clin Invest. 2012 Jun 1;122(6):2306-15. Epub 2012 May 15.

Bryant CD, Kole LA, Guido MA, Sokoloff G, Palmer AA. Congenic dissection of a major QTL for methamphetamine sensitivity implicates epistasis. Genes Brain and Behavior. 2012 Jul;11(5):623-32. Epub 2012 May 2.

Svenson KL, Gatti DM, Valdar W, Welsh CE, Cheng R, Chesler EJ, Palmer AA, McMillan L, Churchill GA. High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics. 2012 Feb;190(2):437-47.

Bartnikas TB, Parker CC, Cheng R, Campagna DR, Lim JE, Palmer AA, Fleming MD. QTLs for murine red blood cell parameters in LG/J and SM/J F(2) and advanced intercross lines. Mamm Genome. 2012 Jun;23(5-6):356-66. Epub 2012 Feb 10.

Carroll AM, Palmer AA, Lionikas A. QTL Analysis of Type I and Type IIA Fibers in Soleus Muscle in a Cross between LG/J and SM/J Mouse Strains. Front Genet. 2011;2:99. Epub 2012 Jan 6.

Parker CC, Palmer AA. Dark matter: are mice the solution to missing heritability? Front Genet. 2011;2:32. Epub 2011 Jun 13.

Hart AB, de Wit H, Palmer AA. Genetic Factors Modulating the Response to Stimulant Drugs in Humans. Curr Top Behav Neurosci. 2012 Jan 20. [Epub ahead of print]

Parker CC, Sokoloff G, Cheng R, Palmer AA. Genome-wide association for fear conditioning in an advanced intercross mouse line. Behav Genet. 2012 May;42(3):437-48. Epub 2012 Jan 12.

Palmer AA, de Wit H. Translational genetic approaches to substance use disorders: bridging the gap between mice and humans. Hum Genet. 2012 Jun;131(6):931-9. Epub 2011 Dec 15. Review.

Bryant CD, Parker CC, Zhou L, Olker C, Chandrasekaran RY, Wager TT, Bolivar VJ, Loudon AS, Vitaterna MH, Turek FW, Palmer AA. Csnk1e is a genetic regulator of sensitivity to psychostimulants and opioids. Neuropsychopharmacology. 2012 Mar;37(4):1026-35. Epub 2011 Nov 16.

Savic D, Distler MG, Sokoloff G, Shanahan NA, Dulawa SC, Palmer AA, Nobrega MA. Modulation of Tcf7l2 expression alters behavior in mice. PLoS One, 2011;6(10):e26897. Epub 2011 Oct 27.

Parker CC, Cheng R, Sokoloff G, Palmer AA. Genome-wide association for methamphetamine sensitivity in an advanced intercross mouse line. Genes Brain Behav, 2012 Feb;11(1):52-61. Epub 2011 Nov 23.

Winawer MR, Seal SR, Phillips AG, Rabinowitz D, Palmer AA. Mapping a Mouse Limbic Seizure Susceptibility Locus on Chromosome 10. Epilepsia, 2011 Nov;52(11):2076-83. Epub 2011 Sep 11.

Cheng R, Abney, M, Palmer AA, Skol A. QTLRel: an R Package for Genome-wide Association Studies in which Relatedness is a Concern. BMC Genet,  2011 Jul 27;12:66.

Johnson LR, McGuire J, Lazarus R, Palmer AA. Pavlovian fear memory circuits and phenotype models of PTSD. Neuropharmacology. 2012 Feb;62(2):638-46. Epub 2011 Jul 19.

Parker CC, Cheng R, Lim JE, Skol AD, Abney M, Palmer AA. Fine-mapping quantitative trait loci for body weight in LG/J x SM/J F2 and F34 advanced intercross lines. Mamm Genome, 2011 Oct;22(9-10):563-71. Epub 2011 Jul 15

Philip VW, Sokoloff G, Ackert-Bicknell C, Striz M, Branstetter L, Beckmann MM, Spence JS, Naswa S, Jackson BL, Galloway LD, Barker P, Wymore AM, Hunsicker PR, Durtschi DC, Shaw GS, Shinpock S, Manly KF, Miller DR, Donahue K, Culiat CT, Churchill GA, Lariviere WR, Palmer AA, O’Hara B, Voy BH, Chesler EJ. Genetic analysis in the Collaborative Cross breeding population: Heritability, genetic correlation and QTL mapping. Genome Res, 2011 Aug;21(8):1223-38. Epub 2011 Jul 6.

Kärst S, Cheng R, Schmitt AO, Yang H, Pardo-Manuel de Villena F, Palmer AA, Brockmann GA. Genetic Determinants for Intramuscular Fat Content and Water Holding Capacity in Mice Selected for High Muscle Mass, Mamm Genome, 2011 Oct;22(9-10):530-43. Epub 2011 Jul 6.

Li D, Herrera S, Bubula N, Nikitina E, Palmer AA, Hanck DA, Loweth JA, Vezina P. Casein kinase 1 enables accumbens amphetamine-induced locomotion by regulating AMPA receptor phosphorylation. J Neurochem, 2011 Jul;118(2):237-47. Epub 2011 Jun 6.

Sokoloff G, Parker CC, Lim JE, Palmer AA. Anxiety and Fear in a cross of C57BL6/J and DBA2/J mice: mapping overlapping and independent QTL for related traits. Genes Brain Behav, 2011 Jul;10(5):604-14. Epub 2011 May 31.

Dlugos AM, Hamidovic A, Hodgkinson C, Shen P, Goldman D, Palmer AA, de Wit H. OPRM1 gene variants modulate amphetamine-induced euphoria in humans. Genes Brain Behav, 2011 Mar;10(2):199-209. Epub 2010 Nov 2.

Palmer AA, Dulawa SC. Murine Warriors or Worriers: The Saga of Comt1, B2 SINE Elements, and the Future of Translational Genetics. Front Neurosci. 2010 Oct 8;4:177.

Swaggart K, Heydemann A, Palmer AA, McNally E. Distinct genetic regions modify specific muscle groups in muscular dystrophy. Physiol Genomics, 2011 Jan 7;43(1):24-31. Epub 2010 Oct 19.

Yang A, Childs E, Palmer AA, de Wit H. More on ADORA. Psychopharmacology (Berl). 2010 Dec;212(4):699-700. Epub 2010 Aug 28.

Lionikas A, Cheng R, Lim JE, Palmer AA, Blizard DA. Fine-mapping of muscle weight QTL in LG/J and SM/J intercrosses. Physiol Genomics, 2010 Sep;42A(1):33-8. Epub 2010 Jul 13.

Samocha KE, Lim JE, Cheng R, Sokoloff G, Palmer AA. Fine mapping of QTL for prepulse inhibition in LG/J and SM/J mice using F2 and advanced intercross lines. Genes Brain Behav, 2010 Oct;9(7):759-67. Epub 2010 Jul 20.

Yang A, Palmer AA, de Wit H. Genetics of caffeine consumption and responses to caffeine. Psychopharmacology (Berl). 2010 Aug;211(3):245-57. Epub 2010 Jun 9.

Cheng R, Lim JE, Samocha KE, Sokoloff G, Abney M, Skol AD, Palmer AA. Genome-wide association studies and the problem of relatedness among advanced intercross lines and other highly recombinant populations. Genetics, 2010 Jul;185(3):1033-44. Epub 2010 May 3.

Hamidovic A, Dlugos A, Palmer AA, de Wit H. Catechol-O-methyltransferase val158met genotype modulates sustained attention in both the drug-free state and in response to amphetamine. Psychiatric Genet, 2010 Jun;20(3):85-92.

Hamidovic A, Dlugos A, Palmer AA, de Wit H. Polymorphisms in Dopamine Transporter (SLC6A3) are Associated with Stimulant Effects of d-Amphetamine: An Exploratory Pharmacogenetic Study Using Healthy Volunteers. Behav Genet 2010 Mar;40(2):255-61. Epub 2010 Jan 21.

Velez L, Sokoloff G, Miczek KA, Palmer AA, Dulawa SC. Differences in aggressive behavior and DNA copy number variants between BALB/cJ and BALB/cByJ substrains. Behav Genet, 2010 Mar;40(2):201-10. Epub 2009 Dec 23.

McCloskey M, Palmer AA, de Wit H. Are attention lapses related to d-amphetamine liking? Psychopharmacology, 2010 Feb;208(2):201-9. Epub 2009 Nov 21.

Dlugos AM, Hamidovic A, Hodgkinson CA, Goldman D, Palmer AA, de Wit H. More aroused, less fatigued: FAAH gene polymorphisms influence acute response to amphetamine. Neuropsychopharmacology, 2010 Feb;35(3):613-22. Epub 2009 Nov 4.