Manuscript accepted in Molecular Psychiatry
The manuscript titled "Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals" was accepted in Molecular Psychiatry.
Authors: Hayley H A Thorpe, Pierre Fontanillas, John J Meredith, Mariela V Jennings, Renata B Cupertino, Shreya R Pakala; 23andMe Research Team; Sarah L Elson, Jibran Y Khokhar, Lea K Davis, Emma C Johnson, Abraham A Palmer, Sandra Sanchez-Roige*.
(Current and past* Palmer Lab members)
Congratulations!
Molecular Psychiatry, 2025, 13 October
DOI: https://doi.org/10.1038/s41380-025-03219-2
Mentioned in:
23andMe blog post "New Genetic Insights Into Cannabis Use"
October 13, 2025
Washington Post "Scientists identify key reason people may use or get addicted to cannabis"
October 13, 2025
UC San Diego Today "Large Genetic Study Links Cannabis Use to Psychiatric, Cognitive and Physical Health"
October 13, 2025
American Psychiatric Association - APA Headlines "Study Examines Common Genetic Traits Of Cannabis Users"
October 14, 2025

Manhattan plots of A) lifetime cannabis use (N=131,895) and B) frequency of cannabis use (N=73,374). The horizontal line represents the significance threshold (p=5.00E-08). Nearest protein-coding genes (<1Mb) to significant loci (red dots) are labelled.
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