Category Archive for : ‘Funding & Grants’

The new NIDA U01 grant, “Characterization of Tandem Repeat and Structural Variants Contributing to Addictive Behaviors in Mice and Rats”, was awarded to MPI’s: Drs. Abraham Palmer, Melissa Gymrek and Jonatahn Sebat. This grant serves to combine the complementary expertise of the MPI’s to produce a large-scale resource for analyzing the effects of complex variation on mouse and rat phenotypes.

Dr. Palmer is a co-investigator on the NIH/NIDA grant received by Dr. Telese, entitled “Decoding the grammar of transcriptional enhancers regulating different stages of opioid use disorder.”
This project’s goal is to investigate transcriptional regulatory networks underlying different stages of the opioid use disorder, using capped small (cs)RNA-seq method of transcriptional initiation profiling in combination with other sensitive profiling techniques.

Dr. Palmer is a co-investigator on the NIH/NIDCD grant received by Dr. Friedman, entitled “The genetic basis for age-related hearing loss in outbred mice.” The goal of this project is to study genetics of the age-related hearing impairment using GWAS in outbred CFW mice.

Dr. Francesca Telese received a NIH/NIDA U01 grant to support her work in HS rats, entitled: “Single-cell resolution analysis of chromatin accessibility and gene expression changes in a model of drug addiction”. Dr. Palmer is a co-investigator on this project. The goal of this project is to use single cell RNASeq to identify changes that are associated with the extended access to oxycodone intravenous self-administration paradigm.

The goal of the center is to use outbred rats to study the genetic basis of drug self-administration and related behavioral traits. More information is available at www.ratgenes.org.

Dr. Palmer is a co-Investigator on the newly awarded R01 titled “Genetic Modulators of Glaucoma”. The PI is Dr. Monika Jablonski (Department of Ophthalmology in the College of Medicine at the University of Tennessee Health Science Center). The grant will be funded by the National Eye Institute to study glaucoma-related traits in HS rats. Dr. Jablonski has been collaborating with NIDA center on a GWAS in outbred rats led by Dr. Palmer. This grant will fund the phenotyping of eyes obtained from the NIDA center. Phenotypes obtained by Dr. Jablonski will

A new R01 grant from the National Eye Institute was awarded to Drs. Monica Jablonski, Abraham Palmer, and several others. The grant is titled, “Genetic Modulators of Glaucoma.”

Dr. Monica Jablonski (Department of Ophthalmology at the University of Tennessee) received the grant to study glaucoma-related traits in HS rats. Dr. Jablonski has been collaborating with the P50 Center, and this grant will fund phenotyping of eye samples and GWAS for glaucoma-related traits.

A new U01 grant from the National Institute on Drug Abuse (NIDA) was awarded to Drs. Abraham Palmer, Dongjun Chung, Roberto Ciccocioppo, Gerard Thomas Hardiman, Peter Kalivas, and Leah Catherine Solberg Woods. The grant is titled “The Genetic Basis of Opioid Dependence Vulnerablility in a Rodent Model.”

Dr. Sandra Sanchez-Roige’s project, titled “CADM2, a cell adhesion molecule, and its association with risk and psychopathology,” was selected for funding by the Brain & Behavior Research Foundation.

The NARSAD Young Investigator Grant provides support for the most promising young scientists conducting neurobiological research. Two year awards are provided to enable promising investigators to either extend research fellowship training or begin careers as independent research faculty. See their website for more information.

Congratulations, Sandra!