The NIDA Core Center of Excellence grant titled, “Center for Genetics, Genomics, and Epigenetics of Substance Use Disorders in Outbred Rats,” has been awarded to Drs. Abraham Palmer, Pejman Mohammadi, Oksana Polesskaya, and Leah Solberg Woods.
Congratulations!
A competitive renewal of the U01 grant “Genetics of novelty seeking and propensity for drug abuse in outbred rats” was awarded to Drs. Huda Akil, Jun Li, and Stanley Watson. Dr. Palmer is Co-I and PI of the subcontract to UC San Diego.
A new R01 grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) was awarded to Dr. Giordano de Guglielmo, with Dr. Abraham Palmer as co-investigator. The 5-year grant is titled “Identification of Genetic Variants that Influence Compulsive Alcohol Intake in Outbred Rats” and will start March 10, 2023 and end on February 29, 2028.
A new R01 grant titled, “A Framework for Translating Polygenic Findings Related to Alcohol Use Disorder Across Species”, has been awarded to Dr. Abraham Palmer as the Project Director. This 5 year grant incudes more than $2.7M starting September 16th, 2022 and ends on August 31st, 2027.
Congrats, Dr. Palmer!
The new NIDA U01 Grant, “Identification of Genetic Variants that Contribute to Compulsive Cocaine Intake in Rats”, has been awarded to Dr. Abraham Palmer and Dr. Olivier George. This grant will fund the behavioral characterization, biobanking, genotyping and GWAS analysis of 2,082 rats over 5 years. The first milestone for this grant is to implement raspberry pi monitoring systems into Dr. George’s machine-learning data pipeline.
Congratulations!
The grant titled, “Integrative Omics Center for Accelerating Neurobiological Understanding of Opioid Addiction”, has been awarded to Drs. Eric Otto Johnson, Abraham Palmer and several others. The goal of the Integrative Omics Center for Accelerating Neurobiological Understanding of Opioid Addiction (ICAN) is to identify the genetic basis for opioid addiction. Dr. Palmer is an MPI for project 3, which seeks to integrate rodent and human studies using statistical genetic approaches and rodent experiments.
Congratulations!
The grant, “Computational methods for allele-specific expression quantification”, was awarded to Dr. Seyoung Kim and Dr. Abraham Palmer. This grant is supported by the Carnegie Mellon University/National Science Foundation.
The major goals of this grant are to develop computational methodology to quantify allele-specific expression from RNA-seq and genotype data to apply to intercross mouse data.
Congratulations!
Drs Abraham Palmer and Sandra Sanchez-Roige receives a 2022-23 pilot grant award for their research on how age will influence wisdom. This grant will fund the first genetic study of wisdom using a rating scale based on a neurobiological model of wisdom; the proposed wisdom scale (SD-WISE) will assess the genetic signature of wisdom from a population of 500,000 subjects from 23andMe.
Congratulations!
Dr. Abraham Palmer has received a $200,000 supplement for the project titled, “Making data from the center for GWAS in out bred rats FAIR and AI/ML ready”. NIDA has provided these funds to improve the AI/ML (Artificial Intelligence/Machine Learning)-readiness of data from the Center for GWAS outbred rats. Additionally, these funds will be used to address important shortcomings in the processing of several large datasets and be used to implement new methods of effective information sharing.
Dr. Palmer is a co-investigator on an NIH/HIDCD grant received by Dr. Rick Friendman, entitled “The genetics of functional decline in the aging vestibular system: A GWAS and gene expression analysis in aging mice and humans.” This project seeks to identify and study the genetic basis of age-related hearing impairment.
