The manuscript, “A natural mutator allele shapes mutation spectrum variation in mice”, was accepted for publication in Nature. Using the BXD recombinant inbred mouse strain, this study aims to identify the loci that impacts germline mutagenesis. Natural variation in the DNA repair gene, Mutyh, was identified to possibly cause the BXD mutator phenotype. Dr. Abraham Palmer and several others are co-authors on this paper. See the manuscript here.
Congrats, Dr. Palmer!