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  • Protocols & Data

By identifying genes that influence behavior we hope to obtain fundamental mechanistic insights into the molecular basis of both health and disease. RELATIONSHIP BETWEEN GENES AND BEHAVIOR Learn more

Manuscript accepted for publication in Frontiers in Behavioral Neuroscience

The manuscript, “Leptin protects against the development and expression of cocaine addiction-like behavior in heterogeneous stock rats”, has been accepted for publication in Frontiers in Behavioral Neuroscience. This study examines the the effect differing bodyweight and blood leptin levels on the vulnerability to addiction like behavior and the impact of exogenous leptin to cocaine seeking in a large heterogenous rat population. Dr. Abraham Palmer and current Palmer lab member, Clara Ortez, are coauthors along with several others. See pre-print here.

Congrats!

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Abraham Palmer February 9, 2022 Palmer Lab News, Publications

Manuscript accepted for publication in Genes, Brain and Behavior

The manuscript, “A mutant allele of Neuronal Membrane Glycoprotein M6-B (Gpm6b) facilitates behavioral flexibility but increases delay discounting”, has been accepted for publication in Genes, Brain and Behavior. Authors include Sandra Sanchez-Roige, Samuel Barnes, Jazlene Mallari, Rebecca Wood, Oksana Polesskaya and Abraham Palmer.

Congratulations!

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Abraham Palmer February 1, 2022 Palmer Lab News, Publications

Manuscript accepted for publication in Nature

The manuscript, “A natural mutator allele shapes mutation spectrum variation in mice”, was accepted for publication in Nature. Using the BXD recombinant inbred mouse strain, this study aims to identify the loci that impacts germline mutagenesis. Natural variation in the DNA repair gene, Mutyh, was identified to possibly cause the BXD mutator phenotype. Dr. Abraham Palmer and several others are co-authors on this paper. See the manuscript here. 

Congrats, Dr. Palmer!

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Abraham Palmer January 28, 2022 Palmer Lab News, Publications

Manuscript accepted for publication in Frontiers Psychiatry

The manuscript, “Genome-wide association study on three behaviors tested in an open field in heterogeneous stock rats identifies multiple loci implicated in psychiatric disorders”, was accepted for publication in Frontiers Psychiatry, section Addictive Disorders. A genome-wide association study (GWAS) of behaviors measured in an open field was conducted in HS rats. 30 genome wide significant quantitative trait loci and 13 candidate genes were identified for these traits. Not only did this study identify genes that were implicated by human GWAS of psychiatry traits, but also observes several novel findings. Current

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Abraham Palmer January 18, 2022 Palmer Lab News, Publications

Article Accepted for publication in Cell Genomics

The article, “Polymorphic SNPs, short tandem repeats and structural variants are responsible for differential gene expression across C57BL/6 and C57BL/10 substrains”, has been accepted for publication in Cell Genomics. This article compares the widely used C57BL/6J inbred mouse strain with closely related C57BL/6 and C57BL/10 sub strains. Whole genome sequencing and RNA-sequencing analysis of these strains yielded several thousand SNPs, INDELs, short tandem repeats (STRs), structural variants and differentially expressed genes. Milad Mortazavi, Dr. Abraham Palmer and several others coauthored this article. See the article here. Congratulations!

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Abraham Palmer January 13, 2022 Publications, Uncategorized

Palmer Lab Holiday Party, 2021

Palmer and Dulawa Lab members gathered to celebrate the holidays and Amanda’s new job as an Assistant Professor in New Mexico! Happy Holidays!

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Abraham Palmer December 16, 2021 Palmer Lab News

Dr. Amanda Barkley-Levenson to start own lab at the University of New Mexico

Dr. Amanda Barkley-Levenson has accepted a position as an Assistant Professor in the Department of Pharmaceutical Sciences at the University of New Mexico Health Sciences Center and will be starting in 2022. Her lab will work on understanding the genetic basis of alcohol use disorder and excessive drinking by translating novel hits from human GWAS into mouse models for comprehensive follow-up and validation.

Congratulations, Amanda!

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Abraham Palmer December 8, 2021 Palmer Lab News

Gabe Barrero joins the Palmer Lab

Gabe Barrero joined the Palmer lab in November 2021 as an information system analyst with a Bachelor of arts in Biology. He is passionate about data science and its application in international development. In his free time Gabe enjoys Brazilian Jiu Jitsu, Muay Thai, biking, cooking and ice cream.

Welcome, Gabe!

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Abraham Palmer November 29, 2021 Palmer Lab News

New Article accepted for publication in Psychological Medicine

The article, “Evaluation of Delay Discounting as a Transdiagnostic Research Domain Criteria Indicator in 1388 General Community Adults” has been accepted for publication in Psychological Medicine. Drs. Abraham Palmer and Sandra Sanchez-Roige are co-authors along with several others. Congratulations!

Final citation: Levitt, E. E., Oshri, A., Amlung, M., Ray, L.A., Sanchez-Roige, S., Palmer, A.A., & MacKillop, J. (in press) Evaluation of Delay Discounting as a Transdiagnostic Research Domain Criteria Indicator in 1388 General Community Adults. Psychological Medicine.

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Abraham Palmer November 24, 2021 Palmer Lab News, Publications

Article accepted for publication in Genome Biology

The article, “Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries”, has recently been accepted for publication in Genome Biology. This study explores the use of polygenic transcriptome risk scores (PTRS) to improve the prediction of transcriptomic data in underrepresented populations. Dr. Abraham Palmer and several others coauthored this article. See the article here. Congratulations, Dr. Palmer!

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Abraham Palmer November 16, 2021 Palmer Lab News, Publications
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Related Websites:

  • RatGenes
  • RatGTEx
  • C-GORD

Abraham Palmer, PhD

Professor & Vice Chair for Basic Research, Department of Psychiatry

PhD, Biomedical Sciences,
University of California San Diego, 1999

BA, Biology,
The University of Chicago, 1992

Biomedical Research Facility II (BRF2); 3A24
9500 Gilman Drive

Mail Code: 0667
La Jolla, CA 92093-0667

Email: [email protected]
Phone: (858) 534-2093
Twitter: @AbePalmer

UCSD Profile
Curriculum Vitae
________________________

Director, NIDA National Center of Excellence for GWAS in Outbred Rats

Location

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Abraham Palmer's office:
BRF2 (Floor 3-A),
Room 3A24

The Palmer Lab:
BRF2 (Floor 3),
Room 3217: Bays FF-JJ

Biomedical Research Facility II

3147 Biomedical Sciences Way
La Jolla, CA 92093

Our mailing address is:
(Note: our physical address is above)
Palmer Lab
9500 Gilman Drive
Mail Code: 0667
La Jolla, CA 92093-0667

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Recent Posts

  • Manuscript accepted in GENETICS
  • Manuscript accepted in Neuropsychopharmacology
  • Sabrina Mi joins the lab
  • Dr. Palmer presents at PAG 30
  • University of Chicago “Career Trek” students visit Palmer Lab
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